It is recommended for promoting the physiological function (peripheral) of the venous, arterial, lymphatic, retinopathy microcirculation, in the treatment of hemorrhoidal syndromes and fissures.
Components and characteristics
Diosmin: it is a flavonoid, a natural substance with ubiquitous distribution in the plant world but contained in significant concentrations in fruits like citrus (lemons, oranges, grapefruits, etc.). It has always been known and proposed in the treatment of venous insufficiency characterized by night cramps, pain, heaviness and swelling in the legs, but this substance also has anti-oedematous, anti-inflammatory and anti-venous activity, making it useful in the presence of hemorrhoids, cellulitis, varicose veins, capillary fragility and related manifestations such as bruises, hematomas and purpura.
Vitamin C: it puts forward its antioxidant activity in this case specifically towards the connective tissue for which it guarantees not only a protective action but also a specifically reparative and regenerative action.
Bilberry: it has long been known that the titrated dry extract of bilberry is able to fight the fragility and the excessive vascular permeability through a well-proven capillary-protective action in both the venous and arterial blood vessels. This action is explained by the fact that the anthocyanins present in the plant complex are able to inhibit the activity of some enzymes (elastase and collagenase) that destroy the collagen and elastic tissues. Several clinical studies have shown that blueberry anthocyanosides reduce capillary damage in a statistically significant manner compared to placebo.
Bromelain 2500 GDU: this proteolytic enzyme carries out important functions in regards to the connective tissue properly said and especially towards fibrin. In fact, Bromelain has important fibrinolytic, anti-aggregating, anti-inflammatory and draining properties, thus favoring the decrease of swelling and pain of the lower limbs, typical in conditions of poor peripheral circulatory capacity.
Sweet clover: the main effect of coumarin present in Sweet Clover is the one made on the lymphatic drainage which is essential to ensure the return of the liquids present in the extracellular space towards the heart. A deficiency of the lymphatic circulation in fact causes these liquids to accumulate in the tissues and, therefore, swelling particularly frequent in the area of the ankles. In addition, coumarin significantly reduces the demolition of catecholamines, particularly vessel adrenaline with consequent improvement in the contractile capacity of blood vessels.
Pennywort: the triterpenic derivatives present in pennywort leaves are particularly useful for the treatment of chronic venous insufficiency. It stimulates the production of collagen by fibroblasts resulting in an increase of fibronectin which is a structural protein, important for the keeping of the venous vessels and of the collagen itself.
Orthosiphon: it is known for its diuretic and purifying action. It increases the volume of urine in a moderate way favoring the excretion of sodium, potassium and also chlorine. The diuretic action of the plant is also due to a decrease in fluid retention by the colloids present in tissues and blood. These effects are very useful also in cases of cellulite, as it is known that the tissue affected by this problem is very rich not only in water but also uric acid.
Common grape vine: together with the bilberry it is one of the most known phytocomplexes and used when an antioxidant, anti-edema and protective action is needed on the microcirculation. The most important components found in the leaves belong to the category of bioflavonoids (anthocyanidins and proanthocyanidins). In particular, the bioflavonoids of the common grape vine perform an intense anti-oxidant and anti-inflammatory activity. Their most important action is carried out on the capillaries where they positively affect vascular permeability. Procyanidins are in fact able to stabilize the collagen fibers and inhibit the catabolic activity of elastase, an enzyme that leads to the degradation of this key protein of connective tissue.